What items do you need to check for epidemic encephalitis? What are the diagnostic methods for epidemic encephalitis?

What items do you need to check for Japanese encephalitis? What are the diagnostic methods for epidemic encephalitis?

What items do you need to check for epidemic encephalitis? What are the diagnostic methods for epidemic encephalitis?

Epidemic encephalitis check

1. Blood picture
The total number of white blood cells is increased, and neutrophils are above 80%. In a few light patients in the late epidemic, the blood picture can be within the normal range.

2. Cerebrospinal fluid
It is colorless and transparent, the pressure is only slightly increased, and the white blood cell count is increased. Neutrophils are predominant in the first 2 to 3 days of the disease, and mononuclear cells increase in the future. The sugar is normal or high, the protein is often slightly elevated, and the chloride is normal. Cerebrospinal fluid examination can be negative in a few cases within 1 to 3 days of the disease.


3. Virus separation
JE virus can be isolated from brain tissue of death patients within 1 week of disease course, and viral antigen can also be found in brain tissue by immunofluorescence (IFT). Viruses are not easily isolated from cerebrospinal fluid or serum.

Epidemic encephalitis diagnosis
Clinical diagnosis relies mainly on comprehensive analysis of epidemiological data, clinical manifestations and laboratory tests. The diagnosis depends on serology and pathogen examination.

1. Epidemiological data
The disease is more common in 7 to 9 months, slightly earlier in the south and slightly later in the north. The incidence of children under the age of 10 is the highest.

2. Main symptoms and signs
Acute onset, high fever, headache, vomiting, lethargy and other performance. Severe patients have symptoms such as coma, convulsions, difficulty swallowing, coughing and respiratory failure. Signs of meningeal irritation, disappearance of shallow reflexes, deep reflex hyperthyroidism, tonic paralysis and positive disease reflexes.

3. Diagnostic criteria

(1) Suspected cases have fever, headache, nausea, vomiting, lethargy, neck resistance, convulsions, etc. in the mosquito bite season in endemic areas.

(2) The confirmed case 1 had a history of mosquito bites in the affected area. 2 high fever, coma, limb spasm, meningeal irritation and brain vertebral body damage (enhanced muscle tone, positive Pap smear). 3 high fever, coma, convulsions, mania, and even death due to respiratory failure, circulatory failure. 4 Positive results were obtained by pathogen or serological examination.

(3) Clinically diagnosed suspected cases plus 1 and 2 or 2, 3, and exclude bacterial meningitis.